The cortical lymphoid nodules are either primary (without germinal center) or secondary (with the germinal center). The result of the germinal center formation is the production of an expanded population of B memory cells and plasma cells. When the lymph node is activated by the lymph-borne antigens, the B lymphocytes at the center of the nodule will develop into larger, less closely-packed lymphoblasts forming pale central areas called germinal centers. The cortical nodules are rounded or oval dense lymphoid nodules formed by B lymphocytes and macrophages. It consists of the cortical lymphoid nodules separated by the cortical lymph sinuses. The outer cortex is situated under the capsule. ParenchymaĬortex can be divided into two regions which are the outer cortex and inner cortex. Reticular connective tissue network supporting the parenchymal cells and the lymph sinuses in its meshes. On reaching the medulla, these trabeculae run in different directions, anastomosing with each other. The lymph node is surrounded by a fibroelastic capsule that sends many perpendicular septa (trabeculae) that divide the cortex into several compartments. In the cut section, the lymph node consists of an outer dense cortex and an inner pale medulla. The lymph node is indented at the hilum where arteries enter while veins and efferent lymphatic vessels leave the lymph node. They are located along the course of the lymphatic vessels. These are kidney-shaped bodies, which filter the lymph. ![]() The lymphatic system can remove excess fluids from body tissues, this process is crucial because water, proteins, and other substances are continuously leaking out of tiny blood capillaries into the surrounding body tissues, when the lymphatic system didn’t drain the excess fluid from the tissues, the lymph fluid would build up in the body’s tissues, and they would swell. The lymphatic system can produce immune cells (such as lymphocytes, monocytes, and antibody-producing cells called plasma cells), It can absorb fatty acids and subsequent transport of fat, chyle, to the circulatory system. It consists of a complex network of lymphoid organs, lymph nodes, lymph ducts, lymph tissues, lymph capillaries, and a network of lymphatic vessels that carry lymph and other substances throughout the body. Blockages, diseases or infections can affect your lymphatic system’s function. The lymphatic system consists of the lymph nodes, spleen, thymus as well as the lymphatic tissue found in the small intestine (Peyer’s patches) and throat (adenoid tonsils, palatine & tubal tonsils), It is a part of your immune system, It has many functions, It can protect your body from illness-causing invaders, maintain body fluid levels, absorb digestive tract fats and remove cellular waste.
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